4.7 Article

Catalytic enantioselective conjugate addition of fluorobis(phenylsulfonyl)methane to enals: synthesis of chiral monofluoromethyl compounds

Journal

CHEMICAL COMMUNICATIONS
Volume -, Issue 32, Pages 4886-4888

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b907399j

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Funding

  1. NSF [CHE-0704015, CHE-0443580]

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A new highly catalytic enantioselective Michael addition of fluorobis(phenylsulfonyl)methane to alpha,beta-unsaturated aldehydes has been developed for the preparation of chiral monofluoromethyl compounds under mild reaction conditions.

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