4.7 Article

One-pot synthesis of cyclic antifreeze glycopeptides

Journal

CHEMICAL COMMUNICATIONS
Volume -, Issue 13, Pages 1641-1643

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b815917c

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Funding

  1. Ministry of Education, Culture, Science, Sports and Technology of Japan

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The first cyclic glycopeptides exhibiting significant antifreeze activity by forming hexagonal-bipyramidal ice crystals, denoted cyclic antifreeze glycopeptides (cyclic AFGPs), were constructed by a one-pot synthesis based on the controlled cyclization reaction of pre-formed small linear glycopeptides.

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