Journal
CHEMICAL COMMUNICATIONS
Volume -, Issue 3, Pages 322-324Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/b816638b
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Funding
- National Outstanding Youth Science Foundation of China [20 525 518]
- National Natural Foundation of China [20 775 005]
- NSF
- NIH
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We report that the hydrogen-bonding pattern in a molecular beacon can be replaced by metal-dependent pairs of Hg2+ and DNA thymine ( T) bases. A molecular beacon based on T-Hg2+-T exhibits a lower background signal and higher thermostability than regular molecular beacons.
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