4.7 Article

Intramolecular cross-coupling of gem-dibromoolefins: a mild approach to 2-bromo benzofused heterocycles

Journal

CHEMICAL COMMUNICATIONS
Volume -, Issue 35, Pages 5236-5238

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b912093a

Keywords

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Funding

  1. Natural Sciences and Engineering Research Council of Canada (NSERC)
  2. University of Toronto
  3. Merck-Frosst Canada for an industrial research chair
  4. Novartis Foundation

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Highly useful halogenated benzofurans and benzothiophenes are prepared from readily available gem-dibromoolefins using a mild, ligand-free copper catalyzed cross-coupling procedure.

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