Journal
CHEMICAL COMMUNICATIONS
Volume -, Issue 23, Pages 3345-3347Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/b905192a
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Funding
- NRF [2073666, 65305, 68338, 45489]
- EDCTP [CT.2004.32040.001]
- Cape Biotech/Lifelab
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Electrochemical impedimetric recognition by anti-mycolic acid antibodies, present in tuberculosis (TB)-positive human serum co-infected with human immunodeficiency virus (HIV), of mycolic acids (MA) integrated into a self-assembled monolayer of N-(2-mercaptoethyl)octadecanamide on a gold electrode is described, proving that the MA-based electrode can satisfactorily discriminate between a TB-positive and a TB-negative serum, thus offering promise as a potential impedimetric immunosensing platform for active tuberculosis.
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