☆ 4.7 Article

In situ, real-time tracking of cell wall topography and nanomechanics of antimycobacterial drugs treated Mycobacterium JLS using atomic force microscopy

CHEMICAL COMMUNICATIONS (2009)

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Journal

CHEMICAL COMMUNICATIONS
Volume -, Issue 45, Pages 7021-7023

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b914605a

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Categories

Chemistry, Multidisciplinary

Funding

  1. New Faculty Start-up Funds
  2. Utah Water Research Laboratory

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Two antimycobacterial drugs ethambutol (EMB) and isoniazid (INH) were found to result in decreases of biomechanical properties including adhesion force, cell wall spring constant, and Young's modulus in Mycobacterium sp. strain JLS (M. JLS).

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