4.7 Article

Enantiomerically pure bicyclo[3.3.1]nona-2,6-diene as the sole source of enantioselectivity in BIPHEP-Rh asymmetric hydrogenation

Journal

CHEMICAL COMMUNICATIONS
Volume -, Issue 41, Pages 5092-5094

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b807669c

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Funding

  1. Schroedinger Foundation (MM)
  2. EPSRC (CB, SG) [EP/E036848/1]
  3. UKIERI (TP)
  4. Engineering and Physical Sciences Research Council [EP/E036848/1] Funding Source: researchfish
  5. EPSRC [EP/E036848/1] Funding Source: UKRI

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In situ resolution of the rapidly racemising diphosphine BIPHEP and its relatives with the cationic Rh complex of (S,S)-bicyclonona-2,6-diene permits the asymmetric hydrogenation of dehydroamino esters.

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