4.7 Article

Interaction of trivalent antimony with a CCHC zinc finger domain: potential relevance to the mechanism of action of antimonial drugs

Journal

CHEMICAL COMMUNICATIONS
Volume -, Issue 39, Pages 4828-4830

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b809186b

Keywords

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Funding

  1. US NSF [CHE0616768]
  2. CNPq
  3. CAPES

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Sb III competes with Zn II for its binding to the CCHC zinc. nger domain of the NCp7 protein of HIV-1, indicating that zinc finger proteins may be targets for antimony-based drugs and thus responsible for their important pharmacological actions.

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