4.7 Article

Design of a novel molecular beacon: modification of the stem with artificially genetic alphabet

Journal

CHEMICAL COMMUNICATIONS
Volume -, Issue 41, Pages 5128-5130

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b811159f

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Funding

  1. National Institutes of Health [R01GM081527, GM66137]
  2. NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM081527, R01GM066137] Funding Source: NIH RePORTER

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A molecular beacon that incorporates components of an artificially expanded genetic information system (AEGIS) in its stem is shown not to be opened by unwanted stem invasion by adventitious standard DNA; this should improve the darkness'' of the beacon in real-world applications.

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