4.7 Article

Stereoselective synthesis of spirocyclopentanones via N-heterocyclic carbene-catalyzed reactions of enals and dienones

Journal

CHEMICAL COMMUNICATIONS
Volume -, Issue 6, Pages 747-749

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b715733a

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Homoenolates generated from enals by nucleophilic heterocyclic carbene (NHC) catalysis undergo a conjugate addition/cyclization sequence with cyclic dienones, culminating in the efficient synthesis of spirocyclopentanones.

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