Journal
CHEMICAL COMMUNICATIONS
Volume -, Issue 27, Pages 3101-3117Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/b800440d
Keywords
-
Categories
Funding
- National Science Council of Republic of China [NSC-96-2113-M-007-020-MY3]
Ask authors/readers for more resources
The feature article surveys the transition metal-catalyzed three-component coupling of allenes and the related allylation reactions. Most of the reactions shown in the article mechanistically proceed via oxidative addition of organic electrophiles to metals, followed by carbometallation of allene and then transmetalation by main group metals or reagents and organometallic reagents. These reactions provide an efficient route for the synthesis of various substituted allyl and vinyl metal reagents and complex organic molecules in highly regio-, stereo- and chemoselective manner in one pot. The metal reagents or pi-allyl-metal intermediates obtained from the reaction are utilized for the allylation of aldehydes, ketones and imines, producing various homoallylic alcohols and amines in a highly regio- and stereoselective manner.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available