4.7 Article

Pyridine-based lanthanide complexes: towards bimodal agents operating as near infrared luminescent and MRI reporters

Journal

CHEMICAL COMMUNICATIONS
Volume -, Issue 48, Pages 6591-6593

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b817343e

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Funding

  1. Institut National du Cancer
  2. La Ligue contre le Cancer, France
  3. National Science Foundation [DBI0352346]
  4. Le Studium (Agency for research and international hosting associate researchers in Region Centre), Orleans, France

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We report two prototype Ln(3+) complexes that address requirements for both MRI and luminescence imaging and we demonstrate that the presence of two H2O molecules bound to the Ln(3+), beneficial for MRI applications of the Gd3+ analogue, is not a major limitation for the development of NIR luminescent agents.

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