4.7 Article

Rational design of an optical adenosine sensor by conjugating a DNA aptamer with split DNAzyme halves

Journal

CHEMICAL COMMUNICATIONS
Volume -, Issue 46, Pages 6161-6163

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b810812a

Keywords

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Funding

  1. National Natural Science Foundation of China [20605019, 20873134]
  2. University of Science and Technology of China
  3. Chinese Academy of Sciences
  4. PCSIRT [IRT0756]

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Split halves of a hemin-binding DNAzyme have been assembled with an anti-adenosine aptamer to build a homogeneous allosteric sensor for adenosine with high selectivity and sensitivity.

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