4.7 Article

A pH sensitive fluorescent cyanine dye for biological applications

Journal

CHEMICAL COMMUNICATIONS
Volume -, Issue 23, Pages 2323-2324

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b007108k

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A pentamethine cyanine dye has been synthesised that is fluorescent when protonated, becoming non-fluorescent upon proton abstraction. The probe has a pK(a) of 7.5, with observable changes in the fluorescent emission properties across a pH range of 6.0-8.0, therefore providing a useful probe for studying pH in biological media.

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