4.7 Article

A protein-supported fluorescent reagent for the highly-sensitive and selective detection of mercury ions in aqueous solution and live cells

Journal

CHEMICAL COMMUNICATIONS
Volume -, Issue 47, Pages 6345-6347

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b815281k

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Funding

  1. NSFC [20773051]
  2. Major State Basic Research Development Program [2007CB808006]
  3. Programs for New Century Excellent Talents in University (NCET)
  4. Natural Science Foundation [20070926-01]
  5. 111 project [B06009]

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A fluorescent sensor, dansyl-L-aspartic acid (1), coupled with BSA was used to specifically detect Hg2+ in a neutral aqueous solution as well as in live cells; the fluorescence emission spectrum underwent an obvious blue shift with an enhancement in fluorescence intensity, and these effects were evident as color changes in fluorescence imaging pictures.

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