4.7 Article

Facile and highly efficient synthesis of fluorinated heterocycles via Prins cyclization in ionic liquid hydrogen fluoride salts

Journal

CHEMICAL COMMUNICATIONS
Volume -, Issue 33, Pages 3876-3878

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b806389c

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Funding

  1. Scientific Research [17073008]
  2. Ministry of Education, Culture, Sports, Science and Technology

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Prins cyclization of homoallylic alcohols, thiols, and amines with various aldehydes in an ionic liquid HF salt (Et4NF center dot 5HF) afforded the corresponding 4-fluorinated heterocycles in excellent yields.

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