Journal
CHEMICAL COMMUNICATIONS
Volume -, Issue 38, Pages 4628-4630Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/b811575c
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Funding
- EPSRC
- Merck Research Laboratories
- NIH [CA-93455]
- NATIONAL CANCER INSTITUTE [R01CA093455, R56CA093455] Funding Source: NIH RePORTER
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A potent dictyostatin-discodermolide hybrid was designed and synthesised; it showed enhanced cell growth inhibitory activity relative to discodermolide in four human cancer cell lines including the Taxol-resistant NCI/ADR-Res cell line.
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