4.7 Article

Chaetoglobins A and B, two unusual alkaloids from endophytic Chaetomium globosum culture

Journal

CHEMICAL COMMUNICATIONS
Volume -, Issue 45, Pages 5978-5980

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b812144c

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Funding

  1. NSFC [20432030, 2080203]
  2. MOST [2006AA0903, 2007AA09Z446]
  3. Thailand Research Fund [RTA5080005, MRG5080267]

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Chaetoglobins A (1) and B (2), two azaphilone alkaloid dimers with an unprecedented skeleton, were characterized from an endophytic fungus Chaetomium globosum with the former ascertained to be a significant cytotoxin valuable for anti-tumor drug discovery.

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