4.7 Article

Sequence recognition and self-sorting of a dipeptide by cucurbit[6]uril and cucurbit[7]uril

Journal

CHEMICAL COMMUNICATIONS
Volume -, Issue 19, Pages 2236-2238

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b719902c

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Funding

  1. National Research Foundation of Korea [R16-2006-082-01001-0] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)

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Cucurbit[7]uril forms very strong complex with zwitterionic dipeptide Phe-Gly with affinity exceeding 10(7) M-1 and effectively recognizes peptide sequence of Phe-Gly over Gly-Phe as well as Tyr-Gly over Gly-Tyr and Trp-Gly over Gly-Trp with relative affinities of 23 000, 18 000 and 2000, respectively.

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