Journal
JOURNAL OF VIROLOGY
Volume 74, Issue 2, Pages 1029-1032Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JVI.74.2.1029-1032.2000
Keywords
-
Categories
Ask authors/readers for more resources
Control of ganglionic herpes simplex virus (HSV) infection depends on CD8(+) cells but not on the death of infected neurons. Primarily, perforin and granzyme B mediate CD8(+) cell cytotoxicity, whereas the in vivo functions of granzyme A, a third granule protein, are unknown, Here, it is shown that granzyme A restricts the interneuronal spread of HSV and significantly influences ganglionic virus load.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available