Journal
JOURNAL OF VIROLOGY
Volume 74, Issue 1, Pages 556-559Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JVI.74.1.556-559.2000
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Measles virus infection induces a profound immunosuppression that can lead to serious secondary infections. Here we demonstrate that measles virus induces tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) mRNA and protein expression in human monocyte-derived dendritic cells. Moreover, measles virus-infected dendritic cells are shown to be cytotoxic via the TRAIL pathway.
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