Related references
Note: Only part of the references are listed.Orally Active Peptidic Bradykinin B1 Receptor Antagonists Engineered from a Cyclotide Scaffold for Inflammatory Pain Treatment
Clarence T. T. Wong et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2012)
Converting Peptides into Drug Leads by Lipidation
L. Zhang et al.
CURRENT MEDICINAL CHEMISTRY (2012)
Engineering of Conotoxins for the Treatment of Pain
Bodil B. Carstens et al.
CURRENT PHARMACEUTICAL DESIGN (2012)
Cyclotides as a basis for drug design
David J. Craik et al.
EXPERT OPINION ON DRUG DISCOVERY (2012)
A comparison of currently available GLP-1 receptor agonists for the treatment of type 2 diabetes
Eduard Montanya
EXPERT OPINION ON PHARMACOTHERAPY (2012)
Natural Products As Sources of New Drugs over the 30 Years from 1981 to 2010
David J. Newman et al.
JOURNAL OF NATURAL PRODUCTS (2012)
Intestinal Permeability of Cyclic Peptides: Common Key Backbone Motifs Identified
Johannes G. Beck et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)
Introducing Lasso Peptides as Molecular Scaffolds for Drug Design: Engineering of an Integrin Antagonist
Thomas A. Knappe et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2011)
Synthesis of cell-permeable stapled peptide dual inhibitors of the p53-Mdm2/Mdmx interactions via photoinduced cycloaddition
Michael M. Madden et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2011)
Engineering pro-angiogenic peptides using stable, disulfide-rich cyclic scaffolds
Lai Y. Chan et al.
BLOOD (2011)
Ribosomal synthesis of backbone macrocyclic peptides
Takayuki Katoh et al.
CHEMICAL COMMUNICATIONS (2011)
Studying protein-protein interactions using peptide arrays
Chen Katz et al.
CHEMICAL SOCIETY REVIEWS (2011)
Protein epitope mimetics as anti-infectives
John A. Robinson
CURRENT OPINION IN CHEMICAL BIOLOGY (2011)
Cyclotides, a Novel Ultrastable Polypeptide Scaffold for Drug Discovery
Andrew Gould et al.
CURRENT PHARMACEUTICAL DESIGN (2011)
Peptide and peptoid foldamers in medicinal chemistry
W. Seth Horne
EXPERT OPINION ON DRUG DISCOVERY (2011)
Identification and Characterization of a New Family of Cell-penetrating Peptides CYCLIC CELL-PENETRATING PEPTIDES
Laura Cascales et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Cellular uptake of cyclotide MCoTI-I follows multiple endocytic pathways
Janette Contreras et al.
JOURNAL OF CONTROLLED RELEASE (2011)
Chemical Re-engineering of Chlorotoxin Improves Bioconjugation Properties for Tumor Imaging and Targeted Therapy
Muharrem Akcan et al.
JOURNAL OF MEDICINAL CHEMISTRY (2011)
Assessing Helical Protein Interfaces for Inhibitor Design
Brooke N. Bullock et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)
On-resin N-methylation of cyclic peptides for discovery of orally bioavailable scaffolds
Tina R. White et al.
NATURE CHEMICAL BIOLOGY (2011)
Synthesis of all-hydrocarbon stapled α-helical peptides by ring-closing olefin metathesis
Young-Woo Kim et al.
NATURE PROTOCOLS (2011)
The biosynthesis of Caryophyllaceae-like cyclic peptides in Saponaria vaccaria L. from DNA-encoded precursors
Janet A. Condie et al.
PLANT JOURNAL (2011)
The Engineering of an Orally Active Conotoxin for the Treatment of Neuropathic Pain
Richard J. Clark et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2010)
A Dual-Labeled Knottin Peptide for PET and Near-Infrared Fluorescence Imaging of Integrin Expression in Living Subjects
Richard H. Kimura et al.
BIOCONJUGATE CHEMISTRY (2010)
Cyclotides: macrocyclic peptides with applications in drug design and agriculture
David J. Craik et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2010)
Update 1 of: Proteases Universally Recognize Beta Strands In Their Active Sites
Praveen K. Madala et al.
CHEMICAL REVIEWS (2010)
Update 1 of: Beta-Strand Mimetics
Wendy A. Loughlin et al.
CHEMICAL REVIEWS (2010)
Cyclotides as templates in drug design
Sonia Troeira Henriques et al.
DRUG DISCOVERY TODAY (2010)
Synthetic therapeutic peptides: science and market
Patrick Vlieghe et al.
DRUG DISCOVERY TODAY (2010)
Naturally occurring circular proteins: distribution, biosynthesis and evolution
Laura Cascales et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2010)
Downsizing human, bacterial, and viral proteins to short water-stable alpha helices that maintain biological potency
Rosemary S. Harrison et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Peptide drugs to target G protein-coupled receptors
Kathrin Bellmann-Sickert et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2010)
An Engineered Knottin Peptide Labeled with 18F for PET Imaging of Integrin Expression
Zheng Miao et al.
BIOCONJUGATE CHEMISTRY (2009)
Engineered Knottin Peptides: A New Class of Agents for Imaging Integrin Expression in Living Subjects
Richard H. Kimura et al.
CANCER RESEARCH (2009)
A new orally available glucagon-like peptide-1 receptor agonist, biotinylated exendin-4, displays improved hypoglycemic effects in db/db mice
Cheng-Hao Jin et al.
JOURNAL OF CONTROLLED RELEASE (2009)
Potent Inhibitors of β-Tryptase and Human Leukocyte Elastase Based on the MCoTI-II Scaffold
Panumart Thongyoo et al.
JOURNAL OF MEDICINAL CHEMISTRY (2009)
Metal Clips That Induce Unstructured Pentapeptides To Be α-Helical In Water
Michelle T. Ma et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2009)
Conotoxins: natural product drug leads
Reena Halai et al.
NATURAL PRODUCT REPORTS (2009)
Exploring beta-Sheet Structure and Interactions with Chemical Model Systems
James S. Nowick
ACCOUNTS OF CHEMICAL RESEARCH (2008)
N-Methylation of Peptides: A New Perspective in Medicinal Chemistry
Jayanta Chatterjee et al.
ACCOUNTS OF CHEMICAL RESEARCH (2008)
Improving oral bioavailability of peptides by multiple N-methylation: Somatostatin analogues
Eric Biron et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2008)
Preparation, characterization, and application of biotinylated and biotin-PEGylated glucagon-like peptide-1 analogues for enhanced oral delivery
Su Young Chae et al.
BIOCONJUGATE CHEMISTRY (2008)
Contemporary strategies for the stabilization of peptides in the α-helical conformation
Laura K. Henchey et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2008)
Engineering Stabilized Vascular Endothelial Growth Factor-A Antagonists: Synthesis, Structural Characterization, and Bioactivity of Grafted Analogues of Cyclotides
Sunithi Gunasekera et al.
JOURNAL OF MEDICINAL CHEMISTRY (2008)
Knottin cyclization: impact on structure and dynamics
Annie Heitz et al.
BMC STRUCTURAL BIOLOGY (2008)
KNOTTIN: the knottin or inhibitor cystine knot scaffold in 2007
Jerome Gracy et al.
NUCLEIC ACIDS RESEARCH (2008)
What have we learnt from Vioxx?
Harlan Krumholz et al.
BMJ-BRITISH MEDICAL JOURNAL (2007)
Conformational flexibility, internal hydrogen bonding, and passive membrane permeability: Successful in silico prediction of the relative permeabilities of cyclic peptides
Taha Rezai et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2006)
Single turn peptide alpha helices with exceptional stability in water
NE Shepherd et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2005)
Over one hundred peptide-activated G protein-coupled receptors recognize ligands with turn structure
JDA Tyndall et al.
CHEMICAL REVIEWS (2005)
Proteases universally recognize beta strands in their active sites
JDA Tyndall et al.
CHEMICAL REVIEWS (2005)
Activation of apoptosis in vivo by a hydrocarbon-stapled BH3 helix
LD Walensky et al.
SCIENCE (2004)
Ziconotide: Neuronal calcium channel blocker for treating severe chronic pain
GP Miljanich
CURRENT MEDICINAL CHEMISTRY (2004)
Conus venoms: A rich source of novel ion channel-targeted peptides
H Terlau et al.
PHYSIOLOGICAL REVIEWS (2004)
Highly ordered structures of peptides by using molecular scaffolds
T Moriuchi et al.
CHEMICAL SOCIETY REVIEWS (2004)
An alpha helix conformationally restricted peptide is recognized by cervical carcinoma patients' sera
JC Calvo et al.
JOURNAL OF MEDICINAL CHEMISTRY (2003)
Clinically validated peptides as templates for de novo peptidomimetic drug design at G-protein-coupled receptors
RM Jones et al.
CURRENT OPINION IN PHARMACOLOGY (2003)
Molecular properties that influence the oral bioavailability of drug candidates
DF Veber et al.
JOURNAL OF MEDICINAL CHEMISTRY (2002)
The synthesis and study of side-chain lactam-bridged peptides
JW Taylor
BIOPOLYMERS (2002)
The first solution stucture of a single α-helical turn.: A pentapeptide α-helix stabilized by a metal clip
MJ Kelso et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2000)
Drug-like properties and the causes of poor solubility and poor permeability
CA Lipinski
JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS (2000)
An all-hydrocarbon cross-linking system for enhancing the helicity and metabolic stability of peptides
CE Schafmeister et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2000)
Share Paper
