Journal
SCHIZOPHRENIA RESEARCH
Volume 44, Issue 3, Pages 213-220Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/S0920-9964(99)00211-X
Keywords
EEG; harmonic; photic driving; resonance; schizophrenia
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Twenty seven drug-free schizophrenic patients and 25 normal controls were studied in an EEG photic driving paradigm with an improved harmonic resolution. Consistent with previous results, the present data show that schizophrenics have lower EEG responses to photic stimulation in alpha frequency. The differences between normal and schizophrenic subjects were distributed across major brain areas except centro-temporal regions. It also demonstrated that I-Hz narrow-pulsed stimulation was feasible in EEG photic driving studies. The enhanced harmonic resolution produced significantly more information in the frequency domain about EEG oscillatory responses to visual stimulus. Using this new technique, the authors showed for the first time that alpha photic driving was a well defined resonant system and that the group differences in harmonic responses were primarily confirmed in the high frequency portion of alpha band, suggesting a peak frequency shift of EEG resonance in schizophrenia. (C) 2000 Elsevier Science B.V. All rights reserved.
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