Journal
CHEMICAL & PHARMACEUTICAL BULLETIN
Volume 61, Issue 12, Pages 1291-1297Publisher
PHARMACEUTICAL SOC JAPAN
DOI: 10.1248/cpb.c13-00652
Keywords
pyrazolyl; isoxazolyl oxadiazole; nitrile imine; nitrile oxide; antioxidant activity
Funding
- Council of Scientific and Industrial Research (CSIR), New Delhi, India
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A new class of mono and bis heterocycles-styrylsulfonylmethyl 1,3,4-oxadiazoles, pyrazolyl/isoxazolyl-1,3,4-oxadiazoles were prepared and studied their antioxidant activity. The compound methyl substituted 2-(p-methylphenylamino-sulfonylmethyl)-5-[Z-(p-methylstyrylsulfonylmethyl)]-1,3,4-oxadiazole displayed slightly higher antioxidant activity than the standard ascorbic acid.
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