Journal
CHEMICAL & PHARMACEUTICAL BULLETIN
Volume 57, Issue 10, Pages 1100-1102Publisher
PHARMACEUTICAL SOC JAPAN
DOI: 10.1248/cpb.57.1100
Keywords
marine-derived fungus; Penicillium sp.; pyrone derivative; gamma-lactone derivative; antibacterial activity; antifungal activity
Funding
- Thailand Research Fund [PHD/0109/2550]
- Ministry of Education
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Two new fungal metabolites, penicipyrone (1), and penicilactone (2), were isolated from the marine-derived fungus Penicillium sp. PSU-F44 along with three known macrolides, (+)-brefeldin A (3), (+)-brefeldin C (4), and 7-oxobrefeldin A (5). Their antimicrobial activities against methicillin-resistant Staphylococcus aureus SK1 and Microsporum gypseum SH-MU-4 were examined.
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