Journal
CHEMICAL & PHARMACEUTICAL BULLETIN
Volume 56, Issue 12, Pages 1722-1724Publisher
PHARMACEUTICAL SOC JAPAN
DOI: 10.1248/cpb.56.1722
Keywords
Dalbergia odorifera; Leguminosae; flavonoid; arylbenzofuran
Funding
- Plant Diversity Research Center of the 2 1 st Century Frontier Research Program [0320401-00]
- Ministry of Science and Technology of the Korean Government
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Two flavonoids, 4,2',5'-trihydroxy-4'-methoxychalcone (1) and (2S)-6,7,4'-trihydroxyflavan (2), along with fourteen known flavonoids and two other known arylbenzofurans were isolated from the heartwood of Dalbergia odorifera. The structure of compounds 1 and 2 were established by spectroscopic (NMR and MS) analyses. Of the isolates, eight compounds (1, 4, 7, 10, 12, 14, 15, 17) were found to have potent protective effect on glutamate-induced oxidative injury in HT22 cells.
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