Journal
CHEMICAL & PHARMACEUTICAL BULLETIN
Volume 56, Issue 10, Pages 1438-1444Publisher
PHARMACEUTICAL SOC JAPAN
DOI: 10.1248/cpb.56.1438
Keywords
Sinocrassula indica; sinocrassoside; aminopeptidase N inhibitor; aldose reductase inhibitor; crassulaceae
Funding
- the 21st COE Program
- Academic Frontier Project
- the Ministry of Education, Culture, Sports, Science and Technology of Japan (MEXT)
- High-tech Research Center Project (2007-2011)
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From the methanolic extract of the whole plant of Sinocrassula indica (Crassulaceae), six new, flavonol glycosides, sinocrassosides B. (1), B, (2), C, (3), 1), (4), D-2 (5), and D., (6), were isolated together with 30 compounds. The structures of 1-6 were elucidated on the basis of chemical and physicochemical evidence. In addition, several constituents were found to show inhibitory effects on aminopeptidase N and aldose reductase.
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