Journal
CHEMICAL & PHARMACEUTICAL BULLETIN
Volume 56, Issue 11, Pages 1617-1620Publisher
PHARMACEUTICAL SOC JAPAN
DOI: 10.1248/cpb.56.1617
Keywords
isatin; 6-amino-uracil; spiro[pyrimidoquinoline-pyrrolopyrimidne]; aqueous media
Funding
- Research Council of Shahid Beheshti University
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A simple, clean and efficient method for the synthesis of spiro[pyrimido[4,5-b]quinoline-5,5'-pyrrolo[2,3-d]pyrimidine]-pentaone derivatives by condensation reaction of 6-amino-uracils and isatins in aqueous media is reported. These products were evaluated in vitro for their antibacterial activities.
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