4.3 Article

Selective hydrolysis of nitriles to amides using NaOH-PEG under microwave irradiation

Journal

SYNTHETIC COMMUNICATIONS
Volume 30, Issue 10, Pages 1713-1718

Publisher

MARCEL DEKKER INC
DOI: 10.1080/00397910008087213

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We describe here an efficient, rapid and selective method for the conversion of nitriles in to their corresponding amides in the presence of PEG-400, aqueous sodium hydroxide system under microwave irradiation.

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