4.3 Article

Selenium(IV) oxide catalyzed oxidation of aldehydes to carboxylic acids with hydrogen peroxide

Journal

SYNTHETIC COMMUNICATIONS
Volume 30, Issue 24, Pages 4425-4434

Publisher

MARCEL DEKKER INC
DOI: 10.1080/00397910008087069

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A convenient method for oxidative transformation of aromatic, heteroaromatic and aliphatic aldehydes into carboxylic acids is presented. It is based on the oxidation of aldehydes in THF using 30% hydrogen peroxide in the presence of 5 molar % of selenium(IV) oxide. The scope and limitation of the method are discussed.

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