Journal
BRITISH JOURNAL OF SURGERY
Volume 87, Issue 3, Pages 338-343Publisher
BLACKWELL SCIENCE LTD
DOI: 10.1046/j.1365-2168.2000.01359.x
Keywords
-
Categories
Ask authors/readers for more resources
Background: Some 30 per cent of patients develop dyspeptic symptoms following antireflux surgery, These symptoms may result from alterations in the motor and sensory function of the proximal stomach. Methods: Proximal gastric motor and sensory function was studied with an electronic barostat in 12 patients with reflux who underwent laparoscopic hemifundoplication, In addition, 24-h pHmetry, gastric emptying (scintigraphy) and vague nerve integrity (pancreatic polypeptide response to hypoglycaemia) were assessed. Fifteen healthy volunteers served as controls. Results: Laparoscopic hemifundoplication significantly decreased total acid exposure rime (P<0.05). Vagus nerve function remained intact in all hut one patient. The mean(s.e.m) lag phase for emptying of solids was significantly shorter after operation than before (15(3) versus 21(3) min; P<0.05), Proximal gastric compliance was not significantly different before and after fundoplication, However, mean(s.e.m.) postprandial relaxation was significantly reduced (P<0.05) after hemifundoplication compared with the value before operation (3341(1105) versus 12 763(3616)nil over 90 min) and in controls (14 567(2358) ml over 90 min). Postprandial fullness was significantly increased after hemifundoplication (P<0.05). Postprandial gastric relaxation correlated with the lag phase for emptying of solids (r=0.55, P<0.02). Conclusion: After hemifundoplication, proximal gastric compliance is not altered but postprandial relaxation is impaired and associated with sensations of fullness and shorter duration of the lag phase for emptying of solids.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available