4.7 Review

Intestinal and hepatic drug transporters: pharmacokinetic, pathophysiological, and pharmacogenetic roles

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

ABCG2 DYSFUNCTION INCREASES SERUM URIC ACID BY DECREASED INTESTINAL URATE EXCRETION

Tappei Takada et al.

NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS (2014)

Article Medical Laboratory Technology

The Effect of ABCG2 Genotype on the Population Pharmacokinetics of Sunitinib in Patients With Renal Cell Carcinoma

Tomoyuki Mizuno et al.

THERAPEUTIC DRUG MONITORING (2014)

Review Pharmacology & Pharmacy

The Roles of MRP2, MRP3, OATP1B1, and OATP1B3 in Conjugated Hyperbilirubinemia

Dietrich Keppler

DRUG METABOLISM AND DISPOSITION (2014)

Review Pharmacology & Pharmacy

Hepatic and Intestinal Drug Transporters: Prediction of Pharmacokinetic Effects Caused by Drug-Drug Interactions and Genetic Polymorphisms

Kenta Yoshida et al.

ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 53, 2013 (2013)

Editorial Material Pharmacology & Pharmacy

Transporters in Drug Development and Clinical Pharmacology

K. M. Giacomini et al.

CLINICAL PHARMACOLOGY & THERAPEUTICS (2013)

Article Pharmacology & Pharmacy

Emerging Transporters of Clinical Importance: An Update From the International Transporter Consortium

K. M. Hillgren et al.

CLINICAL PHARMACOLOGY & THERAPEUTICS (2013)

Editorial Material Pharmacology & Pharmacy

International Transporter Consortium Commentary on Clinically Important Transporter Polymorphisms

K. M. Giacomini et al.

CLINICAL PHARMACOLOGY & THERAPEUTICS (2013)

Review Gastroenterology & Hepatology

The role and pathophysiological relevance of membrane transporter PepT1 in intestinal inflammation and inflammatory bowel disease

Sarah A. Ingersoll et al.

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2012)

Article Pharmacology & Pharmacy

Impact of Genetic Variation in Breast Cancer Resistance Protein (BCRP/ABCG2) on Sunitinib Pharmacokinetics

Tomoyuki Mizuno et al.

DRUG METABOLISM AND PHARMACOKINETICS (2012)

Review Gastroenterology & Hepatology

The bile salt export pump (BSEP) in health and disease

Ralf Kubitz et al.

CLINICS AND RESEARCH IN HEPATOLOGY AND GASTROENTEROLOGY (2012)

Article Gastroenterology & Hepatology

The PepT1-NOD2 Signaling Pathway Aggravates Induced Colitis in Mice

Guillaume Dalmasso et al.

GASTROENTEROLOGY (2011)

Article Pharmacology & Pharmacy

The impact of SLCO1B1 polymorphisms on the plasma concentration of lopinavir and ritonavir in HIV-infected men

Fabiana B. Kohlrausch et al.

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2010)

Article Cardiac & Cardiovascular Systems

Hepatic Metabolism and Transporter Gene Variants Enhance Response to Rosuvastatin in Patients With Acute Myocardial Infarction The GEOSTAT-1 Study

Kristian M. Bailey et al.

CIRCULATION-CARDIOVASCULAR GENETICS (2010)

Article Cardiac & Cardiovascular Systems

Multiple Genetic Loci Influence Serum Urate Levels and Their Relationship With Gout and Cardiovascular Disease Risk Factors

Qiong Yang et al.

CIRCULATION-CARDIOVASCULAR GENETICS (2010)

Article Pharmacology & Pharmacy

ABCG2 Polymorphism Is Associated With the Low-Density Lipoprotein Cholesterol Response to Rosuvastatin

B. Tomlinson et al.

CLINICAL PHARMACOLOGY & THERAPEUTICS (2010)

Review Biotechnology & Applied Microbiology

Membrane transporters in drug development

Kathleen M. Giacomini et al.

NATURE REVIEWS DRUG DISCOVERY (2010)

Review Pharmacology & Pharmacy

ABCG2: A perspective

Robert W. Robey et al.

ADVANCED DRUG DELIVERY REVIEWS (2009)

Article Pharmacology & Pharmacy

ABCG2 Polymorphism Markedly Affects the Pharmacokinetics of Atorvastatin and Rosuvastatin

J. E. Keskitalo et al.

CLINICAL PHARMACOLOGY & THERAPEUTICS (2009)

Article Pharmacology & Pharmacy

Changes in mRNA Expression Levels of Solute Carrier Transporters in Inflammatory Bowel Disease Patients

Kacper A. Wojtal et al.

DRUG METABOLISM AND DISPOSITION (2009)

Article Chemistry, Multidisciplinary

Major SNP (Q141K) Variant of Human ABC Transporter ABCG2 Undergoes Lysosomal and Proteasomal Degradations

Tomoka Furukawa et al.

PHARMACEUTICAL RESEARCH (2009)

Article Pharmacology & Pharmacy

Pharmacogenetic characterization of sulfasalazine disposition based on NAT2 and ABCG2 (BCRP) gene polymorphisms in humans

Y. Yamasaki et al.

CLINICAL PHARMACOLOGY & THERAPEUTICS (2008)

Article Medicine, General & Internal

SLCO1B1Variants and Statin-Induced Myopathy — A Genomewide Study

NEW ENGLAND JOURNAL OF MEDICINE (2008)

Article Biotechnology & Applied Microbiology

Breast cancer resistance protein (ABCG2) and drug disposition:: intestinal expression, polymorphisms and sulfasalazine as an in vivo probe

Bradley L. Urquhart et al.

PHARMACOGENETICS AND GENOMICS (2008)

Article Genetics & Heredity

Variability in human hepatic MRP4 expression: influence of cholestasis and genotype

U. Gradhand et al.

PHARMACOGENOMICS JOURNAL (2008)

Review Biochemistry & Molecular Biology

ABCG2: structure, function and role in drug response

Orsolya Polgar et al.

EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2008)

Article Biochemistry & Molecular Biology

Multidrug transporter ABCG2/breast cancer resistance protein secretes riboflavin (vitamin B2) into milk

Antonius E. van Herwaarden et al.

MOLECULAR AND CELLULAR BIOLOGY (2007)

Review Physiology

The apical conjugate efflux pump ABCC2 (MRP2)

Anne T. Nies et al.

PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2007)

Review Gastroenterology & Hepatology

Genetics of the innate immune response in inflammatory bowel disease

Johan Van Limbergen et al.

INFLAMMATORY BOWEL DISEASES (2007)

Article Oncology

Pharmacogenetics of ABCG2 and adverse reactions to gefitinib

George Cusatis et al.

JOURNAL OF THE NATIONAL CANCER INSTITUTE (2006)

Article Biotechnology & Applied Microbiology

SLCO1B1 polymorphism markedly affects the pharmacokinetics of simvastatin acid

Marja K. Pasanen et al.

PHARMACOGENETICS AND GENOMICS (2006)

Article Medical Laboratory Technology

Role of BCRP 421C>A polymorphism on rosuvastatin pharynacokinetics in healthy Chinese males

Wei Zhang et al.

CLINICA CHIMICA ACTA (2006)

Article Pharmacology & Pharmacy

Cyclosporine markedly raises the plasma concentrations of repaglinide

LI Kajosaari et al.

CLINICAL PHARMACOLOGY & THERAPEUTICS (2005)

Article Pharmacology & Pharmacy

Meta-analysis of the influence of MDR1 C3435T polymorphism on digoxin pharmacokinetics and MDR1 gene expression

B Chowbay et al.

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2005)

Review Biochemistry & Molecular Biology

Peptide transporters: Structure, function, regulation and application for drug delivery

T Terada et al.

CURRENT DRUG METABOLISM (2004)

Review Pharmacology & Pharmacy

Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview

AH Schinkel et al.

ADVANCED DRUG DELIVERY REVIEWS (2003)

Review Biochemistry & Molecular Biology

The superfamily of organic anion transporting polypeptides

B Hagenbuch et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2003)

Article Multidisciplinary Sciences

The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria

JW Jonker et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)

Article Medicine, Research & Experimental

Tissue distribution and induction of human multidrug resistant protein 3

GL Scheffer et al.

LABORATORY INVESTIGATION (2002)

Article Gastroenterology & Hepatology

Up-regulation of basolateral multidrug resistance protein 3 (Mrp3) in cholestatic rat liver

MG Donner et al.

HEPATOLOGY (2001)

Article Biochemistry & Molecular Biology

Molecular identification and characterization of novel members of the human organic anion transporter (OATP) family

I Tamai et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2000)

Article Biochemistry & Molecular Biology

ATP-dependent transport of bile salts by rat multidrug resistance-associated protein 3 (Mrp3)

T Hirohashi et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2000)