Journal
MICROBES AND INFECTION
Volume 2, Issue 11, Pages 1335-1341Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/S1286-4579(00)01287-9
Keywords
major histocompatibility complex; polymorphism; selection; genetic predisposition to disease; infection; virus; cytotoxic T lymphocyte
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The primary function of the major histocompatibility complex (MHC) is to allow the immune system to identify infectious pathogens and eliminate them. Infectious diseases are now thought to be the main selection force that drives and maintains the extraordinary diversity of the MHC. (C) 2000 Editions scientifiques et medicales Elsevier SAS.
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