Journal
GYNECOLOGIC AND OBSTETRIC INVESTIGATION
Volume 50, Issue 3, Pages 149-152Publisher
KARGER
DOI: 10.1159/000010314
Keywords
pregnancy; nausea; prostaglandin E2; interleukin 1-beta; tumour necrosis factor alpha
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This study investigated the aetiology of nausea and vomiting in pregnancy (NVP) in primary care using a new methodology. Eighteen women in early pregnancy had 2 blood samples taken in one 24-hour time period, one when they were symptomatic, and another when they were symptom-free. Maternal serum levels of the candidate agents PGE2, IL-1 beta, and TNF alpha were measured. The study shows a positive relationship between NVP and maternal serum PGE2 levels in early pregnancy. Copyright (C) 2000 S. Karger AG, Basel.
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