Journal
CANCER INVESTIGATION
Volume 19, Issue 8, Pages 812-820Publisher
MARCEL DEKKER INC
DOI: 10.1081/CNV-100107743
Keywords
chemotherapy-induced cognitive deficits; neuropsychological assessment
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Funding
- NCI NIH HHS [P30CA23108] Funding Source: Medline
- NATIONAL CANCER INSTITUTE [P30CA023108] Funding Source: NIH RePORTER
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Adult cancer survivors hate reported experiencing persistent changes in cognitive function following treatment with chemotherapy. Increasing evidence supports the hypothesis that standard-dose chemotherapy can produce cognitive deficits in a subgroup of adult cancer survivors. Although these cognitive changes tend to be subtle deficits in memory, concentration, and the ability to remain focused or organized, these alterations in cognitive ability can have a significant impact on patients' quality of life generally, and on meeting career and educational goals specifically. This manuscript reviews the literature relevant to the cognitive impact of standard-dose chemotherapy in adults, outlines methodological issues related to the study of cognitive functioning in people with cancer, and discusses future directions Jar research in this area.
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