Journal
PHARMACEUTICAL BIOLOGY
Volume 39, Issue 6, Pages 455-459Publisher
SWETS ZEITLINGER PUBLISHERS
DOI: 10.1076/phbi.39.6.455.5885
Keywords
Teucrium stocksianum; analgesic; anti-inflammatory; topical
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Plants belonging to Teucrium sp. (Lamiaceae) are traditionally used to treat painful and inflammatory conditions. In the present study, Teucrium stocksianum, which is found in Arabia, was evaluated for its analgesic and anti-inflammatory properties. Analgesic activity of 10% ethanol extract was evaluated using hot plate method, tail-flick method and acetic acid writhing method. Anti-inflammatory activity was studied using carrageenan induced rat paw edema, cotton-pellet method, and by topical application of the extract on edema. T. stocksianum showed significant (p<0.05) analgesic and anti-inflammatory activities in all the models studied. Topical application of the extract was also shown to be anti-inflammatory. Results support the traditional use of the plant in the treatment of painful, inflammatory conditions.
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