Journal
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS
Volume 12, Issue 1, Pages 15-21Publisher
KARGER
DOI: 10.1159/000051231
Keywords
semantic memory; Alzheimer's disease; left inferior temporal gyrus
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We examined 57 patients with mild Alzheimer's disease by using three kinds of verbal semantic memory tests (category fluency, confrontation naming and generation of verbal definition) and correlated each score with regional cerebral glucose metabolism determined by F-18-fluorodeoxyglucose a nd positron emission tomography, The scores of all three verbal semantic memory tests correlated significantly with regional cerebral glucose metabolism in the left inferior temporal gyrus, even after controlling for the effects of age, sex and educational attainment. In contrast, the scores of the word recall rest did not correlate significantly with regional cerebral glucose metaboliosm in the left inferior temporal gyrus, neither before nor after controlling for these confounders. Our results suggested that the left: inferior temporal lobe contributes to verbal semantic memory. Copyright (C) 2001 S. Karger AG, Basel.
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