Journal
STEREOTACTIC AND FUNCTIONAL NEUROSURGERY
Volume 77, Issue 1-4, Pages 228-232Publisher
KARGER
DOI: 10.1159/000064611
Keywords
epilepsy; thalamus; centromedian; Lennox-Gastaut syndrome; electrical stimulation
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Electrical stimulation of the centromedian thalamic nucleus (ESCM) has been used in cases of difficult to control seizures with multifocal onset in frontal and temporal lobes, as well as in cases of seizures with no evidence of focal onset, such as Lennox-Gastaut syndrome. The stimulation program consists of 1 min stimulation on one side, 4 min interval OFF stimulation and 1 min stimulation on the other side, alternating from one side to the other for 24 h, at 60-130 Hz, 2.5-5.0 V, 0.21-0.45 ms. 49 cases have been treated and followed for periods of 6 months to 15 years. Results indicate that ESCM is highly efficient to control generalized tonic clonic seizures (GTC), atypical absences (AA) and tonic seizures (TS) and less efficient to control complex partial seizures (CxP). Copyright (C) 2002 S. Karger AG, Basel.
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