☆ 4.4 Article

Pyran Formation by an Atypical CYP-Mediated Four-Electron Oxygenation-Cyclization Cascade in an Engineered Aureothin Pathway

CHEMBIOCHEM (2012)

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Journal

CHEMBIOCHEM
Volume 13, Issue 15, Pages 2196-2199

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/cbic.201200406

Keywords

aureothin; AurH; combinatorial biosyntheses; cytochrome P450 monooxygenase; polyketides

Categories

Biochemistry & Molecular Biology Chemistry, Medicinal

Funding

  1. BMBF (GenoMik/GenBioCom)
  2. NIH [AI47818]

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