4.4 Article

Combinatorial Alanine Substitution Enables Rapid Optimization of Cytochrome P450BM3 for Selective Hydroxylation of Large Substrates

Journal

CHEMBIOCHEM
Volume 11, Issue 18, Pages 2502-2505

Publisher

WILEY-BLACKWELL
DOI: 10.1002/cbic.201000565

Keywords

alkaloids; biocatalysis; cytochromes; monosaccharides; steroids

Funding

  1. U.S. National Institutes of Health [1K99M087551-01A1, 2R01 M068664-05A1]
  2. Fundacao Coordenadoria de Aperfeicoamento de Pessoal de Nivel Superior (CAPES) [1756-09-5]
  3. U.S. Department of Energy, Office of Basic Science [DE-FG02-06ER15762]
  4. King Abdullah University of Science and Technology (KAUST) [KUS-F1-028-03]

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