4.3 Article

Efficient procedure for the preparation of amides using polymer-bound reagents

Journal

SYNTHETIC COMMUNICATIONS
Volume 31, Issue 7, Pages 1001-1005

Publisher

MARCEL DEKKER INC
DOI: 10.1081/SCC-100103528

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An effective method for the conversion of acids into amides is presented. The two-step procedure includes the preparation of acid chloride intermediates using Pol-Ph3P and subsequent treatment of these intermediates with amines and polymer-bound base. The amides were accessible in high yields and purities without further purification.

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