The synthesis of novel substituted 2,5-dioxo-1,2,3,4,5,6,7,8-octahydroquinolines without solvent under microwave irradiation

A convenient synthetic method for substituted 2,5-dioxo-1,2,3,4,5,6,7,8-octahydroquinolines is described. Heating Meldrum's acid, dimedone, ammonium acetate and different aromatic aldehydes without a solvent in a microwave irradiation for 2-5 minutes affords 4 in 72-86% yield. The structure of these compounds has been thoroughly studied by x-ray crystallographic analysis.