Serrulatane diterpenes with antimycobacterial activity isolated from the West Indian sea whip Pseudopterogorgia elisabethae

Two new antimycobacterial serrulatane diterpenes, erogorgiaene (3) and 7-hydroxyerogorgiaene (4), and a novel C-40 bisditerpene (5), have been isolated from the West Indian gorgonian octocoral Pseudopterogorgia elisabethae. The structures of compounds 3-5 were determined by spectral (1D and 2D NMR, IR, UV, and HREIMS) analysis.