Journal
ARCHIVES OF DISEASE IN CHILDHOOD
Volume 84, Issue 1, Pages 50-54Publisher
BRITISH MED JOURNAL PUBL GROUP
DOI: 10.1136/adc.84.1.50
Keywords
cystic fibrosis; sleep; oxygen desaturation
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Aim-To investigate whether children with cystic fibrosis under 3 years of age have disordered breathing and episodes of oxygen desaturation during sleep. Methods-We studied 19 infants (9 boys and 10 girls) with cystic fibrosis, mean age 13.1 months (range 3-36 months) and 20 age and sex matched healthy subjects. Patients and controls underwent an overnight polysomnographic study and respiratory function testing on the following morning. Results-Seven patients with ongoing respiratory tract inflammation had disordered breathing and episodes of oxygen desaturation during sleep. Pulse oximetry showed a significantly lower mean oxygen saturation (Sao,) and a higher percentage of total sleep time spent with SaO(2) less than 93% in symptomatic children than in controls. Conclusion-Results suggest that infants and young children with cystic fibrosis and mild airways inflammation (rhinitis, cough, red throat) have episodes of oxygen desaturation during sleep.
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