Journal
CHAOS
Volume 20, Issue 4, Pages -Publisher
AMER INST PHYSICS
DOI: 10.1063/1.3526968
Keywords
-
Categories
Funding
- Japan Society for the Promotion of Science (JSPS)
Ask authors/readers for more resources
We propose a method for achieving an optimal protocol of intermittent androgen suppression for the treatment of prostate cancer. Since the model that reproduces the dynamical behavior of the surrogate tumor marker, prostate specific antigen, is piecewise linear, we can obtain an analytical solution for the model. Based on this, we derive conditions for either stopping or delaying recurrent disease. The solution also provides a design principle for the most favorable schedule of treatment that minimizes the rate of expansion of the malignant cell population. (C) 2010 American Institute of Physics. [doi:10.1063/1.3526968]
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available