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Gait dynamics in Parkinson's disease: Common and distinct behavior among stride length, gait variability, and fractal-like scaling

Journal

CHAOS
Volume 19, Issue 2, Pages -

Publisher

AMER INST PHYSICS
DOI: 10.1063/1.3147408

Keywords

-

Funding

  1. NIH [AG-14100, RR-13622, HD-39838, AG-08812]
  2. European Union Sixth Framework Program [018474-2]
  3. Dynamic Analysis of Physiological Networks (DAPHNet)
  4. SENSACTION-AAL
  5. National Parkinson Foundation

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Parkinson's disease (PD) is a common, debilitating neurodegenerative disease. Gait disturbances are a frequent cause of disability and impairment for patients with PD. This article provides a brief introduction to PD and describes the gait changes typically seen in patients with this disease. A major focus of this report is an update on the study of the fractal properties of gait in PD, the relationship between this feature of gait and stride length and gait variability, and the effects of different experimental conditions on these three gait properties. Implications of these findings are also briefly described. This update highlights the idea that while stride length, gait variability, and fractal scaling of gait are all impaired in PD, distinct mechanisms likely contribute to and are responsible for the regulation of these disparate gait properties. (C) 2009 American Institute of Physics. [DOI: 10.1063/1.3147408]

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