Journal
HUMAN PATHOLOGY
Volume 32, Issue 1, Pages 135-138Publisher
W B SAUNDERS CO
DOI: 10.1053/hupa.2001.20901
Keywords
lymphoepithelioma-like carcinoma; HPV; EBV; cervix
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Lymphoepithelioma-like carcinoma (LELC) of uterine cervix is an uncommon variant of squamous cell carcinoma (SCC). We report here 2 new cases in which DNA sequences from human papilloma virus (HPV) types 16 and 18 were detected by polymerase chain reaction (PCR), To the best of our knowledge, HPV infection has not been previously described in similar cases occuring in European women. Moreover, Epstein-Barr virus (EBV), which is frequently associated with cervical LELC in Asian women, was absent in our 2 cases. These results suggest that HPVs but not EBV can play a role in the pathogenesis of LELC occuring in women originating from Western countries. Copyright (C) 2001 by W.B. Saunders Company.
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