Journal
MAGNETIC RESONANCE IMAGING
Volume 19, Issue 1, Pages 27-32Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/S0730-725X(01)00226-0
Keywords
functional MRI; blood oxygenation level-dependent; spinal cord
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MR imaging of the cervical spinal cord was carried out on volunteers during alternated rest and either motor or sensory stimulation of one hand, in order to detect image intensity changes arising concomitant to neuronal activity. We employed both spin-echo and gradient-echo echo-planar imaging, on the right and left hands, with both symmetric and asymmetric temporal patterns of rest and stimulation. intensity changes correlated with the time course of stimulation were consistently detected, and the magnitude of the intensity changes depended on the duration of stimulation. The activated regions in the spinal cord extended along a column on the side of the body being stimulated and included localized regions on the contralateral side, in agreement with the neural anatomy. (C) 2001 Elsevier Science Inc. All rights reserved.
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