Journal
FREE RADICAL RESEARCH
Volume 34, Issue 6, Pages 639-648Publisher
HARWOOD ACAD PUBL GMBH
DOI: 10.1080/10715760100300531
Keywords
quercetin; flavonoids; dehydroascorbic acid; glutathione; erythrocytes
Categories
Ask authors/readers for more resources
Exposure of rabbit red blood cells to dehydroascorbic acid (DHA) caused a significant decline in glutathione content which was largely prevented by quercetin, whereas it was insensitive to various antioxidants, iron chelators or scavengers of reactive oxygen species. This response was not mediated by chemical reduction of either extracellular DHA or intracellular glutathione disulfide. In addition, the flavonoid did not affect the uptake of DHA or its reduction to ascorbic acid. Rather, quercetin appeared to specifically stimulate downstream events promoting GSH formation.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available