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Modulating the immune response with dendritic cells and their growth factors

Journal

TRENDS IN IMMUNOLOGY
Volume 22, Issue 1, Pages 41-47

Publisher

ELSEVIER SCI LTD
DOI: 10.1016/S1471-4906(00)01794-4

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Funding

  1. NIDDK NIH HHS [DK57655-01] Funding Source: Medline

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Different subsets of dendritic cells (DCs) appear to play a role in determining the specific cytokines secreted by T helper (Th) cells. A model is proposed that links together factors such as the pathogen, microenvironment. DCs andT cells in a mechanism that results in a flexible determination of T-cell polarization.

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